Filling the mitochondrial copper pool
نویسندگان
چکیده
منابع مشابه
A ratiometric fluorescent sensor for the mitochondrial copper pool.
Copper plays a key role in the modulation of cellular function, defence, and growth. Here we present InCCu1, a ratiometric fluorescent sensor for mitochondrial copper, which changes from red to blue emission in the presence of Cu(i). Employing this probe in microscopy and flow cytometry, we show that cisplatin-treated cells have an impaired ability to accumulate copper in the mitochondria.
متن کاملINVESTIGATING THE PHYSICAL AND MECHANICAL PROPERTIES OF HIGH-COPPER AND SILVER DENTAL-FILLING AMALGAM ALLOYS
Abstract: The aim of the present investigation is to study the physical and mechanical characteristics of dental-filling spherical high-copper and silver amalgams and to compare them with a common high-copper domestic unicompositional amalgam. In this study, cylindrical specimens were mechanically condensed according to the ISO 1559:1986 Standard in order to measure the compressive strength, Vi...
متن کاملA method to determine the ball filling, in Miduk copper concentrator SAG mill
The aim of this research work was to investigate on the ball filling estimation of Miduk semi-autogenous (SAG) Mill via an utilized method. Miduk copper concentrator is located in Kerman Province, Iran, and its size reduction stage includes one gyratory crusher which feeds one SAG mill (9.75 dia.(m)*3.88 length(m)) following two parallel ball mills (5dia.(m)*7lenght(m)). After SAG mill, a tromm...
متن کاملMitochondrial deoxyribonucleotides, pool sizes, synthesis, and regulation.
We quantify cytosolic and mitochondrial deoxyribonucleoside triphosphates (dNTPs) from four established cell lines using a recently described method for the separation of cytosolic and mitochondrial (mt) dNTPs from as little as 10 million cells in culture (Pontarin, G., Gallinaro, L., Ferraro, P., Reichard, P., and Bianchi, V. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 12159-12164). In cycling...
متن کاملDecrypting the Mitochondrial Gene Pool of Modern Panamanians
The Isthmus of Panama--the narrow neck of land connecting the northern and southern American landmasses--was an obligatory corridor for the Paleo-Indians as they moved into South America. Archaeological evidence suggests an unbroken link between modern natives and their Paleo-Indian ancestors in some areas of Panama, even if the surviving indigenous groups account for only 12.3% of the total po...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2018
ISSN: 0021-9258
DOI: 10.1074/jbc.h118.001457